HBV Target gene Detail Information

> CALCRL Gene Search Result

Gene Information

Gene Name	CALCRL
Gene ID	10203
Gene Full Name	calcitonin receptor like receptor
Gene Alias	CRLR; CGRPR
Transcripts	ENSG00000064989
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q16602
HGNC ID	HGNC:16709
VEGA ID	OTTHUMG00000132636
OMIM ID	114190
String ID	9606.ENSP00000386972
Drugbank ID	BE0008934
PharmGKB ID	PA26033

Target gene [CALCRL] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009873	chr2	1	8	5	14	View
1014750	chr2	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CALCRL expression and immune infiltrating cell level correlation result in HBV+ samples
CALCRL expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).