HTLV1 Target gene Detail Information

> CALCB Gene Search Result

Gene Information

Gene Name	CALCB
Gene ID	797
Gene Full Name	calcitonin related polypeptide beta
Gene Alias	CALC2; CGRP2; CGRP-II
Transcripts	ENSG00000175868
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Plasma proteins, Predicted secreted proteins
Uniport_ID	P10092
HGNC ID	HGNC:1438
VEGA ID	OTTHUMG00000164629
OMIM ID	114160
String ID	9606.ENSP00000433490
Drugbank ID	BE0002370
PharmGKB ID	PA26030

Target gene [CALCB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000470	chr11	1142	186	169	1497	View
6000471	chr11	1142	186	169	1497	View
6000501	chr11	1138	128	140	1406	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of CALCB expression and immune infiltrating cell level correlation result in HTLV1+ samples
CALCB expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of CALCB expression and immune infiltrating cell level correlation result in HTLV1+ samples
CALCB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).