HPV Target gene Detail Information

> CACNG3 Gene Search Result


Gene Information
Gene Name CACNG3
Gene ID 10368
Gene Full Name calcium voltage-gated channel auxiliary subunit gamma 3
Transcripts ENSG00000006116
Virus HPV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins, Transporters
Uniport_ID O60359
HGNC ID HGNC:1407
VEGA ID OTTHUMG00000131651
OMIM ID 606403
String ID 9606.ENSP00000005284
Drugbank ID BE0009289; BE0004902
PharmGKB ID PA26017
Target gene [CACNG3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5403086 chr16 3 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of CACNG3 expression and immune infiltrating cell level correlation result in HPV+ samples
CACNG3 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of CACNG3 expression and immune infiltrating cell level correlation result in HPV+ samples
CACNG3 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of CACNG3 expression and immune infiltrating cell level correlation result in HPV+ samples
CACNG3 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of CACNG3 expression and immune infiltrating cell level correlation result in HPV+ samples
CACNG3 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of CACNG3 expression and immune infiltrating cell level correlation result in HPV+ samples
CACNG3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).