HTLV1 Target gene Detail Information

> CACNG2 Gene Search Result

Gene Information

Gene Name	CACNG2
Gene ID	10369
Gene Full Name	calcium voltage-gated channel auxiliary subunit gamma 2
Gene Alias	MRD10
Transcripts	ENSG00000166862
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID	Q9Y698
HGNC ID	HGNC:1406
VEGA ID	OTTHUMG00000030612
OMIM ID	602911
String ID	9606.ENSP00000300105
Drugbank ID	BE0005033; BE0005108; BE0004902
PharmGKB ID	PA26016

Target gene [CACNG2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6013866	chr22	12	4	2	18	View
6029892	chr22	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of CACNG2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CACNG2 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of CACNG2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CACNG2 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of CACNG2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CACNG2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).