HBV Target gene Detail Information

> CACNB2 Gene Search Result

Gene Information

Gene Name	CACNB2
Gene ID	783
Gene Full Name	calcium voltage-gated channel auxiliary subunit beta 2
Gene Alias	MYSB; CAVB2; CACNLB2
Transcripts	ENSG00000165995
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters
Uniport_ID	Q08289
HGNC ID	HGNC:1402
VEGA ID	OTTHUMG00000017764
OMIM ID	600003
String ID	9606.ENSP00000320025
Drugbank ID	BE0002354; BE0008715; BE0009739; BE0004902
PharmGKB ID	PA88

Target gene [CACNB2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003301	chr10	22	65	60	147	View
1004264	chr10	26	44	17	87	View
1009940	chr10	4	10		14	View
1012203	chr10	4	3		7	View
1013422	chr10	5			5	View
1400054	chr10	13	1		14	View
1400141	chr10	3	3		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CACNB2 expression and immune infiltrating cell level correlation result in HBV+ samples
CACNB2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).