HBV Target gene Detail Information

> CACNA2D4 Gene Search Result

Gene Information

Gene Name	CACNA2D4
Gene ID	93589
Gene Full Name	calcium voltage-gated channel auxiliary subunit alpha2delta 4
Gene Alias	RCD4
Transcripts	ENSG00000284953
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q7Z3S7
HGNC ID	HGNC:20202
VEGA ID	OTTHUMG00000168111
OMIM ID	608171
String ID	9606.ENSP00000372169
Drugbank ID	BE0009284; BE0004902
PharmGKB ID	PA130546913

Target gene [CACNA2D4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001399	chr12	399	180	158	737	View
1401134	chr12	399	180	158	737	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CACNA2D4 expression and immune infiltrating cell level correlation result in HBV+ samples
CACNA2D4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).