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HBV Target gene Detail Information

> CACNA1S Gene Search Result


Gene Information
Gene Name CACNA1S
Gene ID 779
Gene Full Name calcium voltage-gated channel subunit alpha1 S
Gene Alias MHS5; HOKPP; TTPP1; Cav1.1; HOKPP1; hypoPP; CCHL1A3; CACNL1A3
Transcripts ENSG00000081248
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID Q13698
HGNC ID HGNC:1397
VEGA ID OTTHUMG00000035784
OMIM ID 114208
String ID 9606.ENSP00000355192
Drugbank ID BE0002355; BE0008715; BE0009739; BE0004902
PharmGKB ID PA85
Target gene [CACNA1S] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011132 chr1 9 1 10 View
1012359 chr1 7 7 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CACNA1S expression and immune infiltrating cell level correlation result in HBV+ samples
CACNA1S expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).