HPV Target gene Detail Information

> CACNA1G Gene Search Result


Gene Information
Gene Name CACNA1G
Gene ID 8913
Gene Full Name calcium voltage-gated channel subunit alpha1 G
Gene Alias NBR13; SCA42; Cav3.1; SCA42ND; Ca(V)T.1
Transcripts ENSG00000006283
Virus HPV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels
Uniport_ID O43497
HGNC ID HGNC:1394
VEGA ID OTTHUMG00000162180
OMIM ID 604065
String ID 9606.ENSP00000352011
Drugbank ID BE0000483; BE0008716; BE0004902
PharmGKB ID PA381
Target gene [CACNA1G] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5402133 chr17 3 2 5 View
5403979 chr17 15 96 26 137 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of CACNA1G expression and immune infiltrating cell level correlation result in HPV+ samples
CACNA1G expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of CACNA1G expression and immune infiltrating cell level correlation result in HPV+ samples
CACNA1G expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of CACNA1G expression and immune infiltrating cell level correlation result in HPV+ samples
CACNA1G expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).