Home
Virus
Gene
Disease
Dataset
Download
Help
 
HPV Target gene Detail Information

> CACNA1E Gene Search Result


Gene Information
Gene Name CACNA1E
Gene ID 777
Gene Full Name calcium voltage-gated channel subunit alpha1 E
Gene Alias BII; CACH6; gm139; Cav2.3; CACNL1A6
Transcripts ENSG00000198216
Virus HPV
Gene Type protein coding
HPA Location Info Plasma membrane;Actin filaments;Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels
Uniport_ID Q15878
HGNC ID HGNC:1392
VEGA ID OTTHUMG00000037301
OMIM ID 601013
String ID 9606.ENSP00000356545
Drugbank ID BE0005024; BE0009609; BE0008718; BE0004902
PharmGKB ID PA26009
Target gene [CACNA1E] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5200486 chr1 9 359 21 389 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of CACNA1E expression and immune infiltrating cell level correlation result in HPV+ samples
CACNA1E expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of CACNA1E expression and immune infiltrating cell level correlation result in HPV+ samples
CACNA1E expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of CACNA1E expression and immune infiltrating cell level correlation result in HPV+ samples
CACNA1E expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of CACNA1E expression and immune infiltrating cell level correlation result in HPV+ samples
CACNA1E expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of CACNA1E expression and immune infiltrating cell level correlation result in HPV+ samples
CACNA1E expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of CACNA1E expression and immune infiltrating cell level correlation result in HPV+ samples
CACNA1E expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of CACNA1E expression and immune infiltrating cell level correlation result in HPV+ samples
CACNA1E expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of CACNA1E expression and immune infiltrating cell level correlation result in HPV+ samples
CACNA1E expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).