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HBV Target gene Detail Information

> CACNA1D Gene Search Result


Gene Information
Gene Name CACNA1D
Gene ID 776
Gene Full Name calcium voltage-gated channel subunit alpha1 D
Gene Alias CACH3; CACN4; PASNA; SANDD; Cav1.3; CCHL1A2; CACNL1A2
Transcripts ENSG00000157388
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID Q01668
HGNC ID HGNC:1391
VEGA ID OTTHUMG00000158278
OMIM ID 114206
String ID 9606.ENSP00000288139
Drugbank ID BE0002359; BE0008715; BE0009739; BE0004902
PharmGKB ID PA84
Target gene [CACNA1D] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005318 chr3 4 52 56 View
1402463 chr3 4 52 56 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CACNA1D expression and immune infiltrating cell level correlation result in HBV+ samples
CACNA1D expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).