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HBV Target gene Detail Information

> CACNA1C Gene Search Result


Gene Information
Gene Name CACNA1C
Gene ID 775
Gene Full Name calcium voltage-gated channel subunit alpha1 C
Gene Alias TS; LQT8; CACH2; CACN2; CaV1.2; CCHL1A1; CACNL1A1
Transcripts ENSG00000285479
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID Q13936
HGNC ID HGNC:1390
VEGA ID OTTHUMG00000150243
OMIM ID 114205
String ID 9606.ENSP00000266376
Drugbank ID BE0000430; BE0008715; BE0009739; BE0004902
PharmGKB ID PA83
Target gene [CACNA1C] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006442 chr12 24 13 1 38 View
1006443 chr12 24 13 1 38 View
1006445 chr12 24 13 1 38 View
1006451 chr12 24 13 1 38 View
1006452 chr12 24 13 1 38 View
1006453 chr12 24 13 1 38 View
1006454 chr12 24 13 1 38 View
1006457 chr12 24 13 1 38 View
1006461 chr12 24 13 1 38 View
1006465 chr12 24 13 1 38 View
1006466 chr12 24 13 1 38 View
1007127 chr12 22 8 30 View
1007819 chr12 16 8 24 View
1007832 chr12 16 8 24 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CACNA1C expression and immune infiltrating cell level correlation result in HBV+ samples
CACNA1C expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).