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HTLV1 Target gene Detail Information

> CA13 Gene Search Result


Gene Information
Gene Name CA13
Gene ID 377677
Gene Full Name carbonic anhydrase 13
Gene Alias CAXIII
Transcripts ENSG00000185015
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoli;Nucleoplasm;Vesicles;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q8N1Q1
HGNC ID HGNC:14914
VEGA ID OTTHUMG00000164940
OMIM ID 611436
String ID 9606.ENSP00000318912
Drugbank ID BE0003633; BE0009965
PharmGKB ID PA134891311
Target gene [CA13] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6003304 chr8 149 15 4 168 View
6008789 chr7 39 1 2 42 View
6015119 chr7 14 1 15 View
6017291 chr7 10 1 11 View
6021524 chr7 3 2 1 6 View
6027677 chr7 1 1 2 View
6027796 chr7 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of CA13 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CA13 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of CA13 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CA13 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of CA13 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CA13 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).