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HPV Target gene Detail Information

> CA10 Gene Search Result


Gene Information
Gene Name CA10
Gene ID 56934
Gene Full Name carbonic anhydrase 10
Gene Alias CARPX; CA-RPX; HUCEP-15
Transcripts ENSG00000154975
Virus HPV
Gene Type protein coding
HPA Location Info Vesicles;Predicted to be secreted;
HPA Protein Class Info Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID Q9NS85
HGNC ID HGNC:1369
VEGA ID OTTHUMG00000177544
OMIM ID 604642
String ID 9606.ENSP00000405388
Drugbank ID BE0003631
PharmGKB ID PA25985
Target gene [CA10] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5003340 chr17 3 1 4 View
5400237 chr17 5 5 View
5400238 chr17 4 4 View
5400239 chr17 8 8 View
5400240 chr17 10 1 3 14 View
5401189 chr17 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of CA10 expression and immune infiltrating cell level correlation result in HPV+ samples
CA10 expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of CA10 expression and immune infiltrating cell level correlation result in HPV+ samples
CA10 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of CA10 expression and immune infiltrating cell level correlation result in HPV+ samples
CA10 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of CA10 expression and immune infiltrating cell level correlation result in HPV+ samples
CA10 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of CA10 expression and immune infiltrating cell level correlation result in HPV+ samples
CA10 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of CA10 expression and immune infiltrating cell level correlation result in HPV+ samples
CA10 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of CA10 expression and immune infiltrating cell level correlation result in HPV+ samples
CA10 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).