HBV Target gene Detail Information

> C8A Gene Search Result

Gene Information

Gene Name	C8A
Gene ID	731
Gene Full Name	complement C8 alpha chain
Transcripts	ENSG00000157131
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters
Uniport_ID	P07357
HGNC ID	HGNC:1352
VEGA ID	OTTHUMG00000008306
OMIM ID	120950
String ID	9606.ENSP00000354458
Drugbank ID	BE0008997
PharmGKB ID	PA25951

Target gene [C8A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006693	chr1	27	7	1	35	View
1015659	chr1		2		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of C8A expression and immune infiltrating cell level correlation result in HBV+ samples
C8A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).