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HTLV1 Target gene Detail Information

> C5orf38 Gene Search Result


Gene Information
Gene Name C5orf38
Gene ID 153571
Gene Full Name chromosome 5 open reading frame 38
Gene Alias CEI; IRX2NB
Transcripts ENSG00000186493
Virus HTLV1
Gene Type protein coding
HPA Location Info Golgi apparatus;Vesicles;Predicted to be secreted;
HPA Protein Class Info Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID Q86SI9
HGNC ID HGNC:24226
VEGA ID OTTHUMG00000161741
OMIM ID 610522
String ID 9606.ENSP00000334267
PharmGKB ID PA162380158
Target gene [C5orf38] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6001410 chr5 91 236 121 448 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of C5orf38 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C5orf38 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of C5orf38 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C5orf38 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).