HTLV1 Target gene Detail Information

> C5orf24 Gene Search Result


Gene Information
Gene Name C5orf24
Gene ID 134553
Gene Full Name chromosome 5 open reading frame 24
Transcripts ENSG00000181904
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q7Z6I8
HGNC ID HGNC:26746
VEGA ID OTTHUMG00000129121
String ID 9606.ENSP00000378427
PharmGKB ID PA144596505
Target gene [C5orf24] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6009798 chr5 7 26 2 35 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of C5orf24 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C5orf24 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of C5orf24 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C5orf24 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).