HBV Target gene Detail Information

> C4BPA Gene Search Result


Gene Information
Gene Name C4BPA
Gene ID 722
Gene Full Name complement component 4 binding protein alpha
Gene Alias PRP; C4BP
Transcripts ENSG00000123838
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Plasma proteins, Predicted secreted proteins
Uniport_ID P04003
HGNC ID HGNC:1325
VEGA ID OTTHUMG00000036173
OMIM ID 120830
String ID 9606.ENSP00000356037
Drugbank ID BE0008975
PharmGKB ID PA25905
Target gene [C4BPA] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1400048 chr1 9 9 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of C4BPA expression and immune infiltrating cell level correlation result in HBV+ samples
C4BPA expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).