HTLV1 Target gene Detail Information

> C2orf76 Gene Search Result

Gene Information

Gene Name	C2orf76
Gene ID	130355
Gene Full Name	chromosome 2 open reading frame 76
Gene Alias	AIM29
Transcripts	ENSG00000186132
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q3KRA6
HGNC ID	HGNC:27017
VEGA ID	OTTHUMG00000153298
String ID	9606.ENSP00000386302
PharmGKB ID	PA162379558

Target gene [C2orf76] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000495	chr2	494	417	509	1420	View
6001673	chr2	301	27	42	370	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of C2orf76 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C2orf76 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).