HPV Target gene Detail Information

> C2orf15 Gene Search Result

Gene Information

Gene Name	C2orf15
Gene ID	150590
Gene Full Name	chromosome 2 open reading frame 15
Transcripts	ENSG00000273045
Virus	HPV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8WU43
HGNC ID	HGNC:28436
VEGA ID	OTTHUMG00000130635
String ID	9606.ENSP00000302202
PharmGKB ID	PA134861678

Target gene [C2orf15] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5401136	chr2	17	5		22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE138080 (GEO)	Cervical intraepithelial neoplasia	25	Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE138080
HeatMap of cell type fractions in all samples	Lollipop of C2orf15 expression and immune infiltrating cell level correlation result in HPV+ samples
C2orf15 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of C2orf15 expression and immune infiltrating cell level correlation result in HPV+ samples
C2orf15 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).