HTLV1 Target gene Detail Information

> C2CD2 Gene Search Result


Gene Information
Gene Name C2CD2
Gene ID 25966
Gene Full Name C2 calcium dependent domain containing 2
Gene Alias TMEM24L; C21orf25; C21orf258
Transcripts ENSG00000157617
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9Y426
HGNC ID HGNC:1266
VEGA ID OTTHUMG00000086779
OMIM ID 617581
String ID 9606.ENSP00000369853
PharmGKB ID PA162379018
Target gene [C2CD2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6001752 chr21 249 97 7 353 View
6004694 chr21 40 23 44 107 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of C2CD2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C2CD2 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of C2CD2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C2CD2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).