HTLV1 Target gene Detail Information

> C22orf39 Gene Search Result

Gene Information

Gene Name	C22orf39
Gene ID	128977
Gene Full Name	chromosome 22 open reading frame 39
Transcripts	ENSG00000242259
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6P5X5
HGNC ID	HGNC:27012
VEGA ID	OTTHUMG00000150137
String ID	9606.ENSP00000382474
PharmGKB ID	PA162378995

Target gene [C22orf39] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6018804	chr22	8	1		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of C22orf39 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C22orf39 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of C22orf39 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C22orf39 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).