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HPV Target gene Detail Information

> C21orf62 Gene Search Result


Gene Information
Gene Name C21orf62
Gene ID 56245
Gene Full Name chromosome 21 open reading frame 62
Gene Alias B37; PRED81; C21orf120
Transcripts ENSG00000262938
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID Q9NYP8
HGNC ID HGNC:1305
VEGA ID OTTHUMG00000175286
String ID 9606.ENSP00000444950
PharmGKB ID PA25857
Target gene [C21orf62] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5200285 chr21 38 3 41 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of C21orf62 expression and immune infiltrating cell level correlation result in HPV+ samples
C21orf62 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of C21orf62 expression and immune infiltrating cell level correlation result in HPV+ samples
C21orf62 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of C21orf62 expression and immune infiltrating cell level correlation result in HPV+ samples
C21orf62 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of C21orf62 expression and immune infiltrating cell level correlation result in HPV+ samples
C21orf62 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of C21orf62 expression and immune infiltrating cell level correlation result in HPV+ samples
C21orf62 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).