HBV Target gene Detail Information

> C1R Gene Search Result

Gene Information

Gene Name	C1R
Gene ID	715
Gene Full Name	complement C1r
Gene Alias	EDSPD1
Transcripts	ENSG00000288512
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Predicted to be secreted;
HPA Protein Class Info	Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	P00736
HGNC ID	HGNC:1246
VEGA ID	OTTHUMG00000168149
OMIM ID	613785
String ID	9606.ENSP00000438615
Drugbank ID	BE0002093
PharmGKB ID	PA25635

Target gene [C1R] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002192	chr12	306	3	11	320	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of C1R expression and immune infiltrating cell level correlation result in HBV+ samples
C1R expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).