HIV Target gene Detail Information

> C1GALT1 Gene Search Result

Gene Information

Gene Name	C1GALT1
Gene ID	56913
Gene Full Name	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Gene Alias	C1GALT; T-synthase
Transcripts	ENSG00000106392
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nuclear bodies;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q9NS00
HGNC ID	HGNC:24337
VEGA ID	OTTHUMG00000151912
OMIM ID	610555
String ID	9606.ENSP00000389176
PharmGKB ID	PA134971259

Target gene [C1GALT1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003122	chr7	27	33	9	69	View
4004526	chr7	43			43	View
4007630	chr7	15	3		18	View
4011111	chr7	7			7	View
4011632	chr7	3	3		6	View
4012774	chr7	4			4	View
4016263	chr19				0	View
4100018	chr7				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of C1GALT1 expression and immune infiltrating cell level correlation result in HIV+ samples
C1GALT1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of C1GALT1 expression and immune infiltrating cell level correlation result in HIV+ samples
C1GALT1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).