HPV Target gene Detail Information

> C14orf28 Gene Search Result

Gene Information

Gene Name	C14orf28
Gene ID	122525
Gene Full Name	chromosome 14 open reading frame 28
Gene Alias	DRIP1; DRIP-1; c14_5270
Transcripts	ENSG00000179476
Virus	HPV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q4W4Y0
HGNC ID	HGNC:19834
VEGA ID	OTTHUMG00000170722
String ID	9606.ENSP00000326846
PharmGKB ID	PA134923136

Target gene [C14orf28] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5201154	chr14	3	3		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE140662 (GEO)	Condyloma Acuminatum	8	Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO)	Oropharyngeal squamous cell carcinoma	16	Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO)	Oropharyngeal squamous cell carcinoma	23	Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO)	Oropharyngeal squamous cell carcinoma	36	Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE138080 (GEO)	Cervical intraepithelial neoplasia	25	Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662
HeatMap of cell type fractions in all samples	Lollipop of C14orf28 expression and immune infiltrating cell level correlation result in HPV+ samples
C14orf28 expression: Low -> High

> Dataset: GSE55546
HeatMap of cell type fractions in all samples	Lollipop of C14orf28 expression and immune infiltrating cell level correlation result in HPV+ samples
C14orf28 expression: Low -> High

> Dataset: GSE55544
HeatMap of cell type fractions in all samples	Lollipop of C14orf28 expression and immune infiltrating cell level correlation result in HPV+ samples
C14orf28 expression: Low -> High

> Dataset: GSE55542
HeatMap of cell type fractions in all samples	Lollipop of C14orf28 expression and immune infiltrating cell level correlation result in HPV+ samples
C14orf28 expression: Low -> High

> Dataset: GSE138080
HeatMap of cell type fractions in all samples	Lollipop of C14orf28 expression and immune infiltrating cell level correlation result in HPV+ samples
C14orf28 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of C14orf28 expression and immune infiltrating cell level correlation result in HPV+ samples
C14orf28 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).

> Dataset: GSE140662