HTLV1 Target gene Detail Information

> C12orf73 Gene Search Result

Gene Information

Gene Name	C12orf73
Gene ID	728568
Gene Full Name	chromosome 12 open reading frame 73
Transcripts	ENSG00000204954
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Centrosome;Mitochondria;Plasma membrane;Predicted to be secreted;
HPA Protein Class Info	Predicted secreted proteins
Uniport_ID	Q69YU5
HGNC ID	HGNC:34450
VEGA ID	OTTHUMG00000170119
OMIM ID	618812
String ID	9606.ENSP00000367330
PharmGKB ID	PA164716790

Target gene [C12orf73] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6007970	chr12	13	37		50	View
6007971	chr12	13	37		50	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of C12orf73 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C12orf73 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).