HTLV1 Target gene Detail Information

> C12orf43 Gene Search Result

Gene Information

Gene Name	C12orf43
Gene ID	64897
Gene Full Name	chromosome 12 open reading frame 43
Gene Alias	Custos
Transcripts	ENSG00000157895
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoli;Golgi apparatus;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q96C57
HGNC ID	HGNC:25719
VEGA ID	OTTHUMG00000169150
String ID	9606.ENSP00000437803
PharmGKB ID	PA143485373

Target gene [C12orf43] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6009398	chr12	16	20	1	37	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of C12orf43 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C12orf43 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of C12orf43 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C12orf43 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of C12orf43 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C12orf43 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).