HIV Target gene Detail Information

> BUB1B Gene Search Result

Gene Information

Gene Name	BUB1B
Gene ID	701
Gene Full Name	BUB1 mitotic checkpoint serine/threonine kinase B
Gene Alias	MVA1; SSK1; BUBR1; Bub1A; MAD3L; hBUBR1; BUB1beta
Transcripts	ENSG00000156970
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	O60566
HGNC ID	HGNC:1149
VEGA ID	OTTHUMG00000129877
OMIM ID	602860
String ID	9606.ENSP00000287598
PharmGKB ID	PA82

Target gene [BUB1B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010109	chr15	7		3	10	View
4010831	chr15	1	7		8	View
4013604	chr15	1	2		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of BUB1B expression and immune infiltrating cell level correlation result in HIV+ samples
BUB1B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).