HIV Target gene Detail Information

> BTN3A3 Gene Search Result

Gene Information

Gene Name	BTN3A3
Gene ID	10384
Gene Full Name	butyrophilin subfamily 3 member A3
Gene Alias	BTF3; BTN3.3
Transcripts	ENSG00000111801
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O00478
HGNC ID	HGNC:1140
VEGA ID	OTTHUMG00000014451
OMIM ID	613595
String ID	9606.ENSP00000244519
PharmGKB ID	PA25461

Target gene [BTN3A3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001063	chr6	175	36	11	222	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of BTN3A3 expression and immune infiltrating cell level correlation result in HIV+ samples
BTN3A3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of BTN3A3 expression and immune infiltrating cell level correlation result in HIV+ samples
BTN3A3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).