HIV Target gene Detail Information

> BTN3A1 Gene Search Result

Gene Information

Gene Name	BTN3A1
Gene ID	11119
Gene Full Name	butyrophilin subfamily 3 member A1
Gene Alias	BTF5; BT3.1; CD277; BTN3.1
Transcripts	ENSG00000026950
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O00481
HGNC ID	HGNC:1138
VEGA ID	OTTHUMG00000014449
OMIM ID	613593
String ID	9606.ENSP00000289361
PharmGKB ID	PA25459

Target gene [BTN3A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003337	chr6	54	10		64	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of BTN3A1 expression and immune infiltrating cell level correlation result in HIV+ samples
BTN3A1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of BTN3A1 expression and immune infiltrating cell level correlation result in HIV+ samples
BTN3A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).