HIV Target gene Detail Information

> BTG1 Gene Search Result

Gene Information

Gene Name	BTG1
Gene ID	694
Gene Full Name	BTG anti-proliferation factor 1
Gene Alias	APRO2
Transcripts	ENSG00000133639
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins
Uniport_ID	P62324
HGNC ID	HGNC:1130
VEGA ID	OTTHUMG00000170092
OMIM ID	109580
String ID	9606.ENSP00000256015
PharmGKB ID	PA25450

Target gene [BTG1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000668	chr12	159	166		325	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of BTG1 expression and immune infiltrating cell level correlation result in HIV+ samples
BTG1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of BTG1 expression and immune infiltrating cell level correlation result in HIV+ samples
BTG1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).