HIV Target gene Detail Information

> BRWD3 Gene Search Result

Gene Information

Gene Name	BRWD3
Gene ID	254065
Gene Full Name	bromodomain and WD repeat domain containing 3
Gene Alias	BRODL; MRX93
Transcripts	ENSG00000165288
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q6RI45
HGNC ID	HGNC:17342
VEGA ID	OTTHUMG00000021908
OMIM ID	300553
String ID	9606.ENSP00000362372
PharmGKB ID	PA134900775

Target gene [BRWD3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006312	chrX	2	22	1	25	View
4011815	chrX	6			6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of BRWD3 expression and immune infiltrating cell level correlation result in HIV+ samples
BRWD3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of BRWD3 expression and immune infiltrating cell level correlation result in HIV+ samples
BRWD3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).