HIV Target gene Detail Information

> BRD7 Gene Search Result

Gene Information

Gene Name	BRD7
Gene ID	29117
Gene Full Name	bromodomain containing 7
Gene Alias	BP75; NAG4; CELTIX1
Transcripts	ENSG00000166164
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q9NPI1
HGNC ID	HGNC:14310
VEGA ID	OTTHUMG00000133170
OMIM ID	618489
String ID	9606.ENSP00000378181
PharmGKB ID	PA25417

Target gene [BRD7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002968	chr16	3	19	51	73	View
4004863	chr16	38			38	View
4006783	chr16	19	3	1	23	View
4006872	chr16	15	5	2	22	View
4011209	chr16		7		7	View
4013438	chr16		3		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of BRD7 expression and immune infiltrating cell level correlation result in HIV+ samples
BRD7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of BRD7 expression and immune infiltrating cell level correlation result in HIV+ samples
BRD7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).