HIV Target gene Detail Information

> BRD1 Gene Search Result

Gene Information

Gene Name	BRD1
Gene ID	23774
Gene Full Name	bromodomain containing 1
Gene Alias	BRL; BRPF1; BRPF2
Transcripts	ENSG00000100425
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O95696
HGNC ID	HGNC:1102
VEGA ID	OTTHUMG00000150288
OMIM ID	604589
String ID	9606.ENSP00000216267
PharmGKB ID	PA25413

Target gene [BRD1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001719	chr22	30	69	38	137	View
4006087	chr22	5	3	19	27	View
4007063	chr22	9	12		21	View
4010243	chr22	9			9	View
4010634	chr22	8			8	View
4011471	chr22	4	2	1	7	View
4016394	chr6				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of BRD1 expression and immune infiltrating cell level correlation result in HIV+ samples
BRD1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of BRD1 expression and immune infiltrating cell level correlation result in HIV+ samples
BRD1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).