HTLV1 Target gene Detail Information

> BRAF Gene Search Result

Gene Information

Gene Name	BRAF
Gene ID	673
Gene Full Name	B-Raf proto-oncogene, serine/threonine kinase
Gene Alias	NS7; B-raf; BRAF1; RAFB1; B-RAF1
Transcripts	ENSG00000157764
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Vesicles;Cytosol;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	P15056
HGNC ID	HGNC:1097
VEGA ID	OTTHUMG00000157457
OMIM ID	164757
String ID	9606.ENSP00000288602
Drugbank ID	BE0000634
Drug (Cytoscape Annotation)	Regorafenib;Sorafenib Tosylate;Dasatinib;Pazopanib Hydrochloride;Nilotinib;Dabrafenib;Vemurafenib
PharmGKB ID	PA25408
FDA Approved Drug	Vemurafenib;Dabrafenib;Encorafenib;Atezolizumab;Binimetinib;Cobimetinib;Nivolumab;Pembrolizumab;Trametinib

Target gene [BRAF] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003717	chr7	5	137	3	145	View
6006739	chr7	62	2		64	View

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).