HBV Target gene Detail Information

> BRAF Gene Search Result


Gene Information
Gene Name BRAF
Gene ID 673
Gene Full Name B-Raf proto-oncogene, serine/threonine kinase
Gene Alias NS7; B-raf; BRAF1; RAFB1; B-RAF1
Transcripts ENSG00000157764
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;Cytosol;
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins
Gene Function Oncogene
Uniport_ID P15056
HGNC ID HGNC:1097
VEGA ID OTTHUMG00000157457
OMIM ID 164757
String ID 9606.ENSP00000288602
Drugbank ID BE0000634
Drug (Cytoscape Annotation) Regorafenib;Sorafenib Tosylate;Dasatinib;Pazopanib Hydrochloride;Nilotinib;Dabrafenib;Vemurafenib
PharmGKB ID PA25408
FDA Approved Drug Vemurafenib;Dabrafenib;Encorafenib;Atezolizumab;Binimetinib;Cobimetinib;Nivolumab;Pembrolizumab;Trametinib
Target gene [BRAF] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1012915 chr7 4 1 1 6 View

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).