HIV Target gene Detail Information

> BPGM Gene Search Result

Gene Information

Gene Name	BPGM
Gene ID	669
Gene Full Name	bisphosphoglycerate mutase
Gene Alias	DPGM
Transcripts	ENSG00000172331
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoli rim;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P07738
HGNC ID	HGNC:1093
VEGA ID	OTTHUMG00000155380
OMIM ID	613896
String ID	9606.ENSP00000376840
PharmGKB ID	PA25401

Target gene [BPGM] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001790	chr7	47	26	59	132	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of BPGM expression and immune infiltrating cell level correlation result in HIV+ samples
BPGM expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of BPGM expression and immune infiltrating cell level correlation result in HIV+ samples
BPGM expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).