HIV Target gene Detail Information

> BOP1 Gene Search Result

Gene Information

Gene Name	BOP1
Gene ID	23246
Gene Full Name	BOP1 ribosomal biogenesis factor
Transcripts	ENSG00000285301
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoli rim;Mitotic chromosome;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q14137
HGNC ID	HGNC:15519
VEGA ID	OTTHUMG00000174603
OMIM ID	610596
String ID	9606.ENSP00000455106
PharmGKB ID	PA25398

Target gene [BOP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003702	chr8	55	1		56	View
4003744	chr8	53	2		55	View
4007700	chr8	18			18	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of BOP1 expression and immune infiltrating cell level correlation result in HIV+ samples
BOP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).