HTLV1 Target gene Detail Information

> BOLL Gene Search Result


Gene Information
Gene Name BOLL
Gene ID 66037
Gene Full Name boule homolog, RNA binding protein
Gene Alias BOULE
Transcripts ENSG00000152430
Virus HTLV1
Gene Type protein coding
HPA Location Info Cytosol;Midbody ring;Nucleoli fibrillar center;Plasma membrane;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8N9W6
HGNC ID HGNC:14273
VEGA ID OTTHUMG00000132747
OMIM ID 606165
String ID 9606.ENSP00000314792
PharmGKB ID PA25397
Target gene [BOLL] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6031012 chr2 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of BOLL expression and immune infiltrating cell level correlation result in HTLV1+ samples
BOLL expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of BOLL expression and immune infiltrating cell level correlation result in HTLV1+ samples
BOLL expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of BOLL expression and immune infiltrating cell level correlation result in HTLV1+ samples
BOLL expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).