HTLV1 Target gene Detail Information

> BOC Gene Search Result

Gene Information

Gene Name	BOC
Gene ID	91653
Gene Full Name	BOC cell adhesion associated, oncogene regulated
Gene Alias	CDON2
Transcripts	ENSG00000144857
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Plasma membrane;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Oncogene
Uniport_ID	Q9BWV1
HGNC ID	HGNC:17173
VEGA ID	OTTHUMG00000159305
OMIM ID	608708
String ID	9606.ENSP00000418663
PharmGKB ID	PA143485316

Target gene [BOC] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6009196	chr3	8	30	1	39	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of BOC expression and immune infiltrating cell level correlation result in HTLV1+ samples
BOC expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of BOC expression and immune infiltrating cell level correlation result in HTLV1+ samples
BOC expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of BOC expression and immune infiltrating cell level correlation result in HTLV1+ samples
BOC expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).