HTLV1 Target gene Detail Information

> BNIP3L Gene Search Result

Gene Information

Gene Name	BNIP3L
Gene ID	665
Gene Full Name	BCL2 interacting protein 3 like
Gene Alias	NIX; BNIP3a
Transcripts	ENSG00000104765
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Mitochondria;Nuclear speckles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Predicted membrane proteins, Transporters
Gene Function	Suppressor gene
Uniport_ID	O60238
HGNC ID	HGNC:1085
VEGA ID	OTTHUMG00000099433
OMIM ID	605368
String ID	9606.ENSP00000370003
PharmGKB ID	PA25395

Target gene [BNIP3L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6012788	chr8	21			21	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of BNIP3L expression and immune infiltrating cell level correlation result in HTLV1+ samples
BNIP3L expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of BNIP3L expression and immune infiltrating cell level correlation result in HTLV1+ samples
BNIP3L expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of BNIP3L expression and immune infiltrating cell level correlation result in HTLV1+ samples
BNIP3L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).