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HBV Target gene Detail Information

> BMPR1B Gene Search Result


Gene Information
Gene Name BMPR1B
Gene ID 658
Gene Full Name bone morphogenetic protein receptor type 1B
Gene Alias ALK6; AMDD; BDA2; ALK-6; BDA1D; CDw293
Transcripts ENSG00000138696
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID O00238
HGNC ID HGNC:1077
VEGA ID OTTHUMG00000130991
OMIM ID 603248
String ID 9606.ENSP00000401907
Drugbank ID BE0009369
Drug (Cytoscape Annotation) Dasatinib;Vandetanib;Crizotinib;Pazopanib Hydrochloride
PharmGKB ID PA25387
Target gene [BMPR1B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005607 chr4 23 18 10 51 View
1010407 chr4 1 11 12 View
1016670 chr4 1 1 View
1400499 chr4 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of BMPR1B expression and immune infiltrating cell level correlation result in HBV+ samples
BMPR1B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).