HIV Target gene Detail Information

> BCL9 Gene Search Result


Gene Information
Gene Name BCL9
Gene ID 607
Gene Full Name B cell CLL/lymphoma 9
Gene Alias LGS
Transcripts ENSG00000116128
Virus HIV
Gene Type protein coding
HPA Location Info Nuclear bodies;Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Predicted intracellular proteins
Gene Function Oncogene
Uniport_ID O00512
HGNC ID HGNC:1008
VEGA ID OTTHUMG00000014031
OMIM ID 602597
String ID 9606.ENSP00000234739
PharmGKB ID PA25318
Target gene [BCL9] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002101 chr1 68 19 25 112 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of BCL9 expression and immune infiltrating cell level correlation result in HIV+ samples
BCL9 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of BCL9 expression and immune infiltrating cell level correlation result in HIV+ samples
BCL9 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).