HIV Target gene Detail Information

> BCL7B Gene Search Result


Gene Information
Gene Name BCL7B
Gene ID 9275
Gene Full Name BCL7B, BAF complex component
Transcripts ENSG00000106635
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q9BQE9
HGNC ID HGNC:1005
VEGA ID OTTHUMG00000023412
OMIM ID 605846
String ID 9606.ENSP00000411073
PharmGKB ID PA25315
Target gene [BCL7B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4013336 chr7 3 1 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of BCL7B expression and immune infiltrating cell level correlation result in HIV+ samples
BCL7B expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of BCL7B expression and immune infiltrating cell level correlation result in HIV+ samples
BCL7B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).