HIV Target gene Detail Information

> BCL11A Gene Search Result

Gene Information

Gene Name	BCL11A
Gene ID	53335
Gene Full Name	BCL11A, BAF complex component
Gene Alias	EVI9; CTIP1; DILOS; ZNF856; HBFQTL5; BCL11A-L; BCL11A-S; BCL11a-M; BCL11A-XL
Transcripts	ENSG00000119866
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nuclear bodies;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Gene Function	Oncogene
Uniport_ID	Q9H165
HGNC ID	HGNC:13221
VEGA ID	OTTHUMG00000129420
OMIM ID	606557
String ID	9606.ENSP00000338774
PharmGKB ID	PA25300

Target gene [BCL11A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009553	chr2	11			11	View
4011731	chr2	6			6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of BCL11A expression and immune infiltrating cell level correlation result in HIV+ samples
BCL11A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of BCL11A expression and immune infiltrating cell level correlation result in HIV+ samples
BCL11A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).