HBV Target gene Detail Information

> BCAT1 Gene Search Result


Gene Information
Gene Name BCAT1
Gene ID 586
Gene Full Name branched chain amino acid transaminase 1
Gene Alias BCT1; PP18; BCATC; ECA39; MECA39; PNAS121
Transcripts ENSG00000060982
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID P54687
HGNC ID HGNC:976
VEGA ID OTTHUMG00000169053
OMIM ID 113520
String ID 9606.ENSP00000443459
Drugbank ID BE0000517
PharmGKB ID PA25288
Target gene [BCAT1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1015810 chr12 2 2 View
1015811 chr12 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of BCAT1 expression and immune infiltrating cell level correlation result in HBV+ samples
BCAT1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).