HPV Target gene Detail Information

> BCAR4 Gene Search Result


Gene Information
Gene Name BCAR4
Gene ID 400500
Transcripts ENSG00000262117
Virus HPV
Gene Type ncRNA
HPA Location Info
Gene Function Oncogene
HGNC ID HGNC:22170
VEGA ID OTTHUMG00000177469
OMIM ID 613746
lncRNASNP2 ID NONHSAG018621.2
PharmGKB ID PA145008949
Target gene [BCAR4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5000635 chr16 96 16 2 114 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of BCAR4 expression and immune infiltrating cell level correlation result in HPV+ samples
BCAR4 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of BCAR4 expression and immune infiltrating cell level correlation result in HPV+ samples
BCAR4 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of BCAR4 expression and immune infiltrating cell level correlation result in HPV+ samples
BCAR4 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of BCAR4 expression and immune infiltrating cell level correlation result in HPV+ samples
BCAR4 expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of BCAR4 expression and immune infiltrating cell level correlation result in HPV+ samples
BCAR4 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of BCAR4 expression and immune infiltrating cell level correlation result in HPV+ samples
BCAR4 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of BCAR4 expression and immune infiltrating cell level correlation result in HPV+ samples
BCAR4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).