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HBV Target gene Detail Information

> BAX Gene Search Result


Gene Information
Gene Name BAX
Gene ID 581
Gene Full Name BCL2 associated X, apoptosis regulator
Gene Alias BCL2L4
Transcripts ENSG00000087088
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Predicted intracellular proteins, Transporters
Gene Function Suppressor gene & Oncogene
Uniport_ID Q07812
HGNC ID HGNC:959
VEGA ID OTTHUMG00000160476
OMIM ID 600040
String ID 9606.ENSP00000293288
PharmGKB ID PA25269
Target gene [BAX] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005268 chr19 29 28 57 View
1005269 chr19 29 28 57 View
1401609 chr19 29 28 57 View
1401610 chr19 29 28 57 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of BAX expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
BAX expression: Low -> High
Lollipop of BAX expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of BAX expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of BAX expression and immune infiltrating cell level correlation result in HBV+ samples
BAX expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).