HTLV1 Target gene Detail Information

> B4GALNT3 Gene Search Result


Gene Information
Gene Name B4GALNT3
Gene ID 283358
Gene Full Name beta-1,4-N-acetyl-galactosaminyltransferase 3
Transcripts ENSG00000139044
Virus HTLV1
Gene Type protein coding
HPA Location Info Golgi apparatus;Vesicles;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q6L9W6
HGNC ID HGNC:24137
VEGA ID OTTHUMG00000129283
OMIM ID 612220
String ID 9606.ENSP00000266383
PharmGKB ID PA142672564
Target gene [B4GALNT3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6015813 chr12 13 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of B4GALNT3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
B4GALNT3 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of B4GALNT3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
B4GALNT3 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of B4GALNT3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
B4GALNT3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).