HBV Target gene Detail Information

> AXIN2 Gene Search Result

Gene Information

Gene Name	AXIN2
Gene ID	8313
Gene Full Name	axin 2
Gene Alias	AXIL; ODCRCS
Transcripts	ENSG00000168646
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Plasma membrane;Cytosol;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q9Y2T1
HGNC ID	HGNC:904
VEGA ID	OTTHUMG00000179353
OMIM ID	604025
String ID	9606.ENSP00000302625
PharmGKB ID	PA25196

Target gene [AXIN2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007249	chr17	17	12		29	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of AXIN2 expression and immune infiltrating cell level correlation result in HBV+ samples
AXIN2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).