HBV Target gene Detail Information

> AXIN2 Gene Search Result


Gene Information
Gene Name AXIN2
Gene ID 8313
Gene Full Name axin 2
Gene Alias AXIL; ODCRCS
Transcripts ENSG00000168646
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Plasma membrane;Cytosol;
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q9Y2T1
HGNC ID HGNC:904
VEGA ID OTTHUMG00000179353
OMIM ID 604025
String ID 9606.ENSP00000302625
PharmGKB ID PA25196
Target gene [AXIN2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007249 chr17 17 12 29 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of AXIN2 expression and immune infiltrating cell level correlation result in HBV+ samples
AXIN2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).